基本情况

姓名:李厚金

性别:男

民族:汉族

学位:博士

职称:副教授

籍贯:江西宁都

职务:化学国家级实验教学示范中心副主任、化学实验教研室主任。

 

联系方式

电话: 15918685140

电子邮箱:ceslhj@mail.sysu.edu.cn

通讯地址:广东省广州市广州大学城外环东路132号永利集团3044noc登录入口化材综合楼

邮编:510006

 

教育经历
1999年9月-2002年6月,永利集团3044noc登录入口化学与化学工程学院有机化学专业,博士
1996年9月-1999年6月,永利集团3044noc登录入口化学与化学工程学院有机化学专业,硕士
1992年9月-1996年6月,南昌大学化学与化工学院,本科

 

工作经历
2002年7月至今,永利集团3044noc登录入口。 
2005年10月至2006年9月,在美国加州大学圣克鲁兹分校(University of California at Santa Cruz)做访问学者,从事海洋生物活性物质研究。 

 

讲授课程

广东省一流本科课程、永利集团3044noc登录入口一流本科课程“基础化学实验(有机)”课程负责人。主讲本科生课程“基础化学实验(有机)”和“实验室安全与学术道德”。主讲研究生课程“有机分离与结构分析”、“论文写作、学术道德与实验室安全”和“实验室与生物安全”。

 

科研方向
主要开展天然产物研究与开发。具体研究方向有: 
(1)海洋微生物,包括细菌、真菌等产生的新结构化合物的发现和药物应用; 
(2)南海海洋生物的代谢产物及其应用研究; 
(3)陆源植物、特色中草药的药用成分研究与开发; 
(4)微生物生物转化的研究与应用。

 

科研项目

近年来,主持承担有国家自然科学基金项目、广东省科技计划项目、广东省自然科学基金项目、广州市科技计划项目、广东中医药强省科研项目、中央高校基本科研业务费专项基金项目、企业委托项目等20余项。 

 

获奖情况

2008年获广东省科学技术一等奖(获奖名称:南海海洋微生物及其代谢产物研究,排名第6)。

2021年广东省教育教学成果一等奖(排名第5)。

2021年永利集团3044noc登录入口校级教学成果一等奖(排名第5)。

2021、2019、2017年获永利集团3044noc登录入口校级教学成果二等奖共3项(排名第1)。

2021年负责的课程基础化学实验(有机)”获广东省本科高校在线教学优秀课程案例二等奖(排名第1)。

2020年,主讲的《实验室安全与学术道德》课程获广东省本科高校课程思政优秀案例二等奖(排名第2)。

2019年、2022年指导学生参加第一、第三届全国大学生化学实验创新设计竞赛获竞赛特等奖2项、华南赛区一等奖1项。

 

论著一览

主要科研论文:

  1. Hui-Xian Liang, Meng-Jiao Hao, Guang-Yu Zhang, Hou-Jin Li, Wen-Zhe Ma, Jun Xu, Wen-Jian Lan. Lentinuses A-B, two alkaloids from the marine-derived fungus Lentinus sajor-caju with potent anti-pulmonary fibrosis activity. Fitoterapia, 2023, 166, 105433.
  2. Qin Huang, Meng-Jiao Hao, Lai-You Wang, Feng Wu, Hou-Jin Li, Jie Yuan, Jun Xu, Taifo Mahmud, Wen-Jian Lan. Isolation and stereospecific synthesis of indole alkaloids with lipid-lowering effects from the marine-derived fungus Colletotrichum gloeosporioides BB4. Phytochemistry, 2023, 209, 113612.
  3. Xiao-Ming Dai, Hui-Lin Pan, Wen-Jian Lan, Liu-Ping Chen, Gong-Kan Feng, Rong Deng, Xiao-Feng Zhu, Hou-Jin Li*. Indole alkaloids fusarindoles A-E from marine-derived fungus Fusarium equiseti LJ-1. Phytochemistry, 2022, 204, 113456.
  4. Meng-Jiao Hao, Pei-Nan Chen, Hou-Jin Li, Feng Wu, Guang-Yu Zhang, Zong-Ze Shao, Xiu-Pian Liu, Wen-Zhe Ma, Jun Xu, Taifo Mahmud, Wen-Jian Lan. β-Carboline alkaloids from the deep-sea fungus Trichoderma sp. MCCC 3A01244 as a new type of anti-pulmonary fibrosis agents that inhibit TGF-β/Smad signaling pathway. Frontiers in Microbiology, 2022, 13, 947226.
  5. Ming-Jun Hong, Meng-Jiao Hao, Guang-Yu Zhang, Hou-Jin Li, Zong-Ze Shao, Xiu-Pian Li, Wen-Zhe Ma, Jun Xu, Taifo Mahmud, Wen-Jian Lan. Exophilone, a tetrahydrocarbazol-1-one analogue with anti-pulmonary fibrosis activity from the deep-sea fungus Exophiala oligosperma MCCC 3A01264. Marine Drugs, 2022, 20(7), 448.
  6. Pei-Nan Chen, Meng-Jiao Hao, Hou-Jin Li, Jun Xu, Taifo Mahmud, Wen-Jian Lan. Biotransformations of anthranilic acid and phthalimide to potent antihyperlipidemic alkaloids by the marine-derived fungus Scedosporium apiospermum F41-1. Bioorganic Chemistry, 2021, 116, 105375.
  7. Xiao-Jing Liu, Hou-Jin Li, Wen-Zhe Ma, Fu-Ming Zhang, Meng-Yang Xu, Taifo Mahmud, Wen-Jian Lan*. Phomaligols F–I, Polyoxygenated cyclohexenone derivatives from marine-derived fungus Aspergillus flavus BB1. Bioorganic Chemistry, 2021, 115, 105269.
  8. Qin Huang, Hou-Jin Li, Chang-Bai Huang, Zi-Han Wang, Wen-Jian Lan, Lai-You Wang. Alkaloids from the marine fungus Lecanicillium fusisporum using an amino acid-directed strategy. Natural Product Communications, 2021, 16(10), 1-6.
  9. Sharpkate Shaker, Run-Zhu Fan, Hou-Jin Li*, Wen-Jian Lan*. A pair of novel bisindole alkaloid enantiomers from marine fungus Fusarium sp. XBB-9. Natural Product Research, 2021, 35(9), 1497-1503.
  10. Qi Guo, Xiao-Ming Dai, Wen-Jian Lan, Liu-Ping Chen, Chi-Keung Lam, Gong-Kan Feng, Rong Deng, Xiao-Feng Zhu, and Hou-Jin Li*. Monascuslactams A–D, cytotoxic γ-lactams from marine fungus Monascus albidus BB3. Natural Product Research, 2021, 36 (10), 2534-2541.
  11. Qi Guo, Wen‐Jian Lan, Liu‐Ping Chen, Chi‐Keung Lam, Gong‐Kan Feng, Rong Deng, Xiao‐Feng Zhu, Hou‐Jin Li*. Monalbidins A–E, decalins with potential cytotoxic activities from marine derived fungus Monascus albidus BB3. Chemistry and Biodiversity, 2021, 18, e2100068.
  12. Sharpkate Shaker, Ting-Ting Sun, Liang-Yue Wang, Wen-Zhe Ma, Dong-Lan Wu, Yong-Wei Guo, Jun Dong, Yan-Xiu Chen, Long-Ping Zhu, De-Po Yang*, Hou-Jin Li*, Wen-Jian Lan*. Reactive oxygen species altering the metabolite profile of the marine-derived fungus Dichotomomyces cejpii F31-1. Natural Product Research, 2021, 35(1), 41–48.
  13. Yong-Wei Guo, Xiao-Jing Liu, Jie Yuan, Hou-Jin Li,Taifo Mahmud, Ming-Jun Hong, Jian-Chen Yu, Wen-Jian Lan*. L-Tryptophan induces a marine-derived Fusarium sp. to produce indole alkaloids with activity against the Zika virus. Journal of Natural Products, 2020, 83(11), 3372-3380.
  14. Chan-Juan Li, Pei-Nan Chen, Hou-Jin Li, Taifo Mahmud, Dong-Lan Wu, Jun Xu, Wen-Jian Lan*. Potential antidiabetic fumiquinazoline alkaloids from the marine-derived fungus Scedosporium apiospermum F41‑1. Journal of Natural Products, 2020, 83(4), 1082-1091.
  15. Yong-Wei Guo, Ben-Qiang Gong, Jie Yuan, Hou-Jin Li, Taifo Mahmud, Yun Huang, Jian-Feng Li, De-Po Yang, Wen-Jian Lan*. L‑phenylalanine alters the privileged secondary metabolite production in the marine-derived fungus Trichoderma erinaceum F1‑1. Journal of Natural Products, 2020, 83(1), 79−87.
  16. Yi Qiu, Qi Guo, Yan-Qin Ran, Wen-Jian Lan, Chi-Keung Lam, Gong-Kan Feng, Rong Deng, Xiao-Feng Zhu, Hou-Jin Li*, Liu-Ping Chen*. Cytotoxic alkaloids from the marine shellfish-associated fungus Aspergillus sp. XBB-4 induced by amino acid-directed strategy. RSC Advances, 2020, 10(8), 4243-4250.
  17. Yan-Qin Ran, Wen-Jian Lan, Yi Qiu, Qi Guo, Gong-Kan Feng, Rong Deng, Xiao-Feng Zhu, Hou-Jin Li*, Jun Dong*. Monarubins A–C from the marine shellfish-associated fungus Monascus ruber BB5. Marine Drugs, 2020, 18(2), 100.
  18. Mei-xiang Yuan, Qi Guo, Yan-qin Ran, Yi Qiu, Wen-jian Lan, Hou-jin Li. New aromadendrane sesquiterpenoid pseuboydone F from the marine-derived fungus Pseudallescheria boydii F44-1. Records of Natural Products, 2020, 14(3), 166-170.
  19. Mei-Xiang Yuan, Yi Qiu, Yan-Qin Ran, Gong-Kan Feng, Rong Deng, Xiao-Feng Zhu, Wen-Jian Lan, Hou-Jin Li. Exploration of indole alkaloids from marine fungus Pseudallescheria boydii F44-1 using an amino acid-directed strategy. Marine Drugs, 2019, 17(2), 77.
  20. Hou-Jin Li, Cai-Wu Jiang (共同第一), Meng-Yang Xu (共同第一), Dan-Feng Yan, Dong-Lan Wu, Xia-Fu-Kai-Ti Xia-Ke-Er, Yong-Wei Guo, Jun Xu, De-Po Yang and Wen-Jian Lan. Pseudapenes A−C, sesquiterpenoids from the marine-derived fungus Pseudallescheria apiosperma F52-1. Tetrahedron Letters, 2019, 60(34), 150953.
  21. Dong-Lan Wu, Hou-Jin Li, Duncan R. Smith, Janejira Jaratsittisin, Xia-Fu-Kai-Ti Xia-Ke-Er, Wen-Zhe Ma, Yong-Wei Guo, Jun Dong, Juan Shen, De-Po Yang*, Wen-Jian Lan*. Polyketides and alkaloids from the marine-derived fungus Dichotomomyces cejpii F31-1 and the antiviral activity of scequinadoline A against Dengue Virus. Marine Drugs 2018, 16(7), 229.
  22. Lei Huang, Wen-Jian Lan, Hou-Jin Li*. Two new hirsutane-type sesquiterpenoids chondrosterins N and O from the marine fungus Chondrostereum sp.. Natural Product Research, 2018, 32(13), 1578-1582.
  23. Yi Qiu, Wen-Jian Lan, Hou-Jin Li*, Liu-Ping Chen*. Linear Triquinane sesquiterpenoids: their isolation, structures, biological activities and chemical synthesis. Molecules, 2018, 23(9), 2095.
  24. Yan-Xiu Chen, Meng-Yang Xu, Hou-Jin Li, Kun-Jiao Zeng, Wen-Zhe Ma, Guo-Bao Tian, Jun Xu, De-Po Yang, Wen-Jian Lan. Diverse secondary metabolites from the marine-derived fungus Dichotomomyces cejpii F31-1. Marine Drugs, 2017, 15(11), 339.
  25. Li-Hong Huang, Meng-Yang Xu(共同第一), Hou-Jin Li (共同第一), Jin-Qian Li, Yan-Xiu Chen, Wen-Zhe Ma, Yi-Ping Li, Jun Xu, De-Po Yang, and Wen-Jian Lan*. Amino acid-directed strategy for inducing the marine-derived fungus Scedosporium apiospermum F41–1 to maximize alkaloid diversity. Organic Letters. 2017, 19(18), 4888−4891.
  26. Li-Hong Huang, Yan-Xiu Chen, Jian-Chen Yu, Jie Yuan, Hou-Jin Li, Wen-Zhe Ma, Ramida Watanapokasin, Kun-Chao Hu, Shah Iram Niaz, De-Po Yang, Wen-Jian Lan. Secondary metabolites from the marine-derived fungus Dichotomomyces sp. L-8 and their cytotoxic activity. Molecules, 2017, 22, 444.
  27. Qing-Xiang Cao, Jun-Hua Wei, Rong Deng, Gong-Kan Feng, Xiao-Feng Zhu, Wen-Jian Lan*, Hou-Jin Li*. Two new pyripyropenes from the marine fungus Fusarium sp. 2016F18-1. Chemistry and Biodiversity,2017, 14(3), e1600298.
  28. Ting Chen, Chi-Keung Lam, Wen-Dan Chen, Xiao-Hong Chen, Gong-Kan Feng, Xiao-Feng Zhu, Wen-Jian Lan*, Hou-Jin Li*. NMR screening approach for discovery of new 6-methylpyridinone derivatives from the marine-derived fungus Leptosphaerulina sp.. Arabian Journal of Chemistry, 2017, 10(2), 288-294.
  29. Kun-Chao Hu, Meng-Yang Xu, Hou-Jin Li, Jie Yuan, Ge Tang, Jun Xu, De-Po Yang and Wen-Jian Lan*. Discovery of aromadendrane anologues from the marine-derived fungus Scedosporium dehoogii F41-4 by NMR-guided isolation. RSC Advances, 2016, 6(97), 94763–94770.
  30. Kun-Teng Wang, Meng-Yang Xu, Wei Liu, Hou-Jin Li, Jun Xu, De-Po Yang, Wen-Jian Lan, Lai-You Wang*. Two additional new compounds from the marine-derived fungus Pseudallescheria ellipsoidea F42-3. Molecules, 2016, 21(4), 442.
  31. Wen-Jian Lan, Kun-Teng Wang, Meng-Yang Xu, Jing-Jing Zhang, Chi-Keung Lam, Guo-Hua Zhong, Jun Xu,De-Po Yang, Hou-Jin Li*, Lai-You Wang*. Secondary metabolites with chemical diversity from the marine-derived fungus Pseudallescheria boydii F19-1 and their cytotoxic activity. RSC Advances, 2016, 6(80), 76206-76213.
  32. Lei Huang, Wen-Jian Lan, Rong Deng, Gong-Kan Feng, Qing-Yan Xu, Zhi-Yu Hu, Xiao-Feng Zhu*, Hou-Jin Li*. Additional new cytotoxic triquinane-type sesquiterpenoids chondrosterins K–M from the marine fungus Chondrostereum sp.. Marine Drugs, 2016, 14(9), 157.
  33. Wen-Jian Lan, Sheng-Jiao Fu, Meng-Yang Xu, Wan-Ling Liang, Chi-Keung Lam, Guo-Hua Zhong, Jun Xu, De-Po Yang, Hou-Jin Li. Five new cytotoxic metabolites from the marine fungus Neosartorya pseudofischeri. Marine Drugs, 2016, 14(1), 18.
  34. Wei Liu, Hou-Jin Li (共同第一), Meng-Yang Xu (共同第一), Ying-Chen Ju, Lai-You Wang, Jun Xu, De-Po Yang, and Wen-Jian Lan. Pseudellones A–C, three alkaloids from the marine-derived fungus Pseudallescheria ellipsoidea F42–3. Organic Letters, 2015, 17(21), 5156-5159.
  35. Dan-Feng Yan, Wen-Jian Lan, Kun-Teng Wang, Lei Huang, Cai-Wu Jiang*, Hou-Jin Li*. Two chlorinated benzofuran derivatives from marine fungus Pseudallescheria boydii. Natural Product Communications, 2015, 10(4), 621-622.
  36. 王坤腾, 王来友, 蓝文健, 颜丹凤, 李厚金. 海洋真菌对苯和甲苯的降解诱导黄烷酮的羟基化转化. 2015, 32(6), 671-675.
  37. 刘威,梁婉玲,谢中梁,蓝文健,李厚金,杨得坡,王来友. 南海长棘海星共附生真菌的分离鉴定及多样性分析。永利集团3044noc登录入口学报(自然科学版), 2015, 54 (1), 84-88.
  38. Wan-Ling Liang, Xiu Le, Hou-Jin Li, Xiang-Ling Yang, Jun-Xiong Chen,Jun Xu, Huan-Liang Liu, Lai-You Wang, Kun-Teng Wang, Kun-Chao Hu, De-Pong Yang, Wen-Jian Lan. Exploring the chemodiversity and biological activities of the secondary metabolites from the marine fungus Neosartorya pseudofischeri. Marine Drugs, 2014, 12(11), 5657-5676.
  39. Wen-Jian Lan, Wei Liu, Wan-Ling Liang, Zeng Xu, Xiu Le, Jun Xu, Chi-Keung Lam, De-Po Yang, Hou-Jin Li, Lai-You Wang. Pseudaboydins A and B, novel isobenzofuranone derivatives from marine fungus Pseudallescheria boydii associated with starfish Acanthaster planci. Marine Drugs, 2014, 12 (7), 4188-4199.
  40. Zeng Xu, Lei Huang, Xiao-Hong Chen, Xiao-Feng Zhu, Xiao-Jun Qian , Gong-Kan Feng, Wen-Jian Lan, Hou-Jin Li. Cytotoxic prenylated xanthones from the pericarps of Garcinia mangostana. Molecules, 2014, 19(2), 1820-1827.
  41. Hou-Jin Li, Wen-Han Jiang, Wan-Ling Liang, Jia-Xin Huang, Yu-Fei Mo, Yan-Qing Ding, Chi-Keung Lam, Xiao-Jun Qian, Xiao-Feng Zhu, Wen-Jian Lan. Induced marine fungus Chondrostereum sp. as a means of producing new sesquiterpenoids Chondrosterins I and J by using glycerol as the carbon source. Marine Drugs, 2014, 12(1), 167-175.
  42. Hou-Jin Li, Ting Chen, Ying-Lu Xie, Wen-Dan Chen, Xiao-Feng Zhu, Wen-Jian Lan. Isolation and structure elucidation of Chondrosterins F–H from the marine fungus Chondrostereum sp.. Marine Drugs, 2013, 11(2), 551-558.
  43. Zhong-Liang Xie, Hou-Jin Li*, Lai-You Wang, Wan-Ling Liang, Wei Liu, Wen-Jian Lan. Trichodermaerin, a novel diterpenoid lactone from the marine fungus Trichoderma erinaceum associated with seastar Acanthaster planci. Natural Product Communications, 2013, 8(1), 67-68.
  44. 赵骁宇,徐增,蓝文健,李厚金。山竹的化学成分及其呫吨酮类化合物的药理作用研究进展。中草药,2013,44(8),1052-1061。
  45. Yang Zhao, Shu-Qing Li, Hou-Jin Li*, Wen-Jian Lan. Lanostane triterpeoids from the fungus Ceriporia lacerate associated with Acanthaster planci. Chemistry of Natural Compounds, 2013, 49(4), 653-656.
  46. Fen Yang, Wen-Dan Chen, Rong Deng, Hui Zhang, Jun Tang, Ke-Wei Wu, Dan-Dan Li, Gong-Kan Feng, Wen-Jian Lan, Hou-Jin Li*, Xiao-Feng Zhu. Hirsutanol A, a novel sesquiterpene compound from fungus Chondrostereum sp., induces apoptosis and inhibits tumor growth through mitochondrial-independent ROS production: Hirsutanol A inhibits tumor growth through ROS production. Journal of Translational Medicine, 2013, 11: 32.
  47. Wen-Jian Lan, Yang Zhao, Zhong-Liang Xie, Li-Zhen Liang, Wei-Yan Shao, Long-Ping Zhu, De-Po Yang, Xiao-Feng Zhu, Hou-Jin Li*. Novel sorbicillin analogues from the marine fungus Trichoderma sp. associated with the seastar Acanthaster planci. Natural Product Communications, 2012, 7(10), 1337-1340.
  48. 马建国,李厚金,邓蓉,冯公侃,朱孝峰。干扰Nrf2可增强Hirsutanols A对肿瘤细胞增殖的抑制作用。南方医科大学学报,2012,32(8),1093-1097.
  49. Hou-Jin Li, Da-Lang Zhou, Ting-Juan Xu, Chi-Keung Lam, Wen-Jian Lan. 5,6,7,5’-Tetramethoxy-3’,4’-methylenedioxyflavone monohydrate. Acta Cryst. (2012). E68, o1390.
  50. 赵阳,梁丽珍,李厚金,文诗雅,蓝文健。威灵仙的化学成分研究。永利集团3044noc登录入口学报自然科学版,2012, 51 (3), 63-67。
  51. Fen Yang, Wen-Dan Chen, Deng Rong, Dan-Dan Li, Ke-Wei Wu, Gong-Kan Feng, Hou-Jin Li*, Xiao-Feng Zhu. Hirsutanol A induces apoptosis and autophagy via reactive oxygen species accumulation in breast cancer MCF-7 cells. Journal of Pharmacological Sciences, 2012, 119(3), 214-220.
  52. Hou-jin Li, Ying-lu Xie, Zhong-liang Xie, Ying Chen, Chi-Keung Lam, Wen-jian Lan. Chondrosterins A–E, triquinane-type sesquiterpenoids from soft coral-associated fungus Chondrostereum sp.. Marine Drugs, 2012, 10(3), 627-638.
  53. 王丰,李厚金,蓝文健. 软珊瑚Sarcophyton tortuosum共生真菌Penicillium sp.的代谢产物研究。永利集团3044noc登录入口学报(自然科学版), 2011, 50(6), 72-77.
  54. 李厚金,蓝文健. 天然单萜柠檬烯的微生物转化研究进展. 化学进展,2011, 23(11), 2318-2325.
  55. Hou-Jin Li, Wen-Jian Lan*, Chi-keung Lam, Fen Yang, Xiao-Feng Zhu.  Hirsutane sesquiterpenoids from the marine-derived fungus Chondrostereum sp.. Chemistry and Biodiversity, 2011, 8(2), 317-324.
  56. 李厚金,谢莹璐,邱小忠,蓝文健. α-蒎烯促进海洋真菌Aspergillus sp.产真菌毒素青霉酸的研究. 永利集团3044noc登录入口学报,2011, 50(2), 66-69.
  57. 吴克伟,杨芬,刘俊龄,冯公侃,李厚金,朱孝峰. Hirsutanols A通过增加活性氧选择性诱导多西他赛耐药非小细胞肺癌细胞PC14/TXT凋亡. 中国药理学通报,2010, 26(8), 1005-1010.
  58. Hou-Jin Li, Yong-Tong Cai, Yun-Yun Chen, Chi-keung Lam, Wen-Jian Lan*. Metabolites of marine fungus Aspergillus sp. collected from soft coral Sarcophyton tortuosum. Chemical Research in Chinese Universities, 2010, 26 (3), 415-419.
  59. Fen Yang, You-Heng Gao, Ke-Wei Wu, Rong Deng, Dan-Dan Li, Zhi-Xiong Wei, Shan Jiang, Xiao-Qi Wu, Gong-Kan Feng, Hou-Jin Li, Xiao-Feng Zhu. A novel sesquiterpene Hirsutanol A induces autophagical cell death in human hepatocellular carcinoma cells by increasing reactive oxygen species. Chinese Journal of Cancer, 2010, 29(7), 655-660.
  60. Wen-Jian Lan, Shou-Liang Wang, Hou-Jin Li*. Additional New Tetracyclic Tetraterpenoid, Methyl Tortuoate D from Soft Coral Sarcophyton tortuosum. Natural Product Communications, 2009, 4(9), 1193-1196.
  61. 李厚金,李淑青,王丰,蓝文健. 长棘海星体内的脂肪酸成分及其生物学意义分析. 永利集团3044noc登录入口学报,2009, 48(5), 55-60.
  62. 黎国喜, 李厚金, 杨中艺, 辛国荣, 唐湘如, 袁剑刚. “黑麦草-水稻”草田轮作系统的根际效应. V.意大利黑麦草(Lolium multiflorum)根茬腐解物中存在促水稻生长活性物质的证据. 永利集团3044noc登录入口学报(自然科学版),2008,47(4), 88-93.
  63. Li, Guoxi, Zeng, Ren Sen, Li, Houjin, Yang, Zhongyi, Xin, Guorong, Yuan, Jiangang, Luo, Yi . Allelopathic effects of decaying Italian ryegrass (Lolium mutiflorum Lam.) residues on rice. Allelopathy Journal, 2008, 22(1), 15-23.
  64. Wen-Jian Lan, Lin-Feng Mo, Chuang-Hua Cai, Yi-Pin Zhou, Jun-Hua Yao, Hou-Jin Li*. Studies on Culture Condition of New Marine Bacterium Zooshikella sp. SY01. Frontiers of Chemical Engineering in China, 2008, 2(4), 443-446.
  65. Wen-Jian Lan, Hong-Ping Wan, Guo-Xi Li, Hou-Jin Li*, Yun-Yun Chen, Cheng-Zhu Liao, Ji-Wen Cai. New Sesquiterpene Formamides from the Marine Sponge Axinyssa sp.. Helvetica Chimica Acta, 2008, 91(3), 426-434.
  66. Hou-Jin Li, Taro Amagata, Karen Tenney, Phillip Crews. Additional Scalarane Sesterterpenes from the Sponge Phyllospongia papyracea. Journal of Natural Products, 2007, 70(5), 802-807.
  67. Wen-Jian Lan, Hou-Jin Li *. New Sesterterpenoids from the Sponge Phyllospongia papyracea. Helvetica Chimica Acta, 2007, 90(6), 1218-1222.
  68. Wen-Jian Lan, Hou-Jin Li, Su-Jun Yan, Jing-Yu Su, Long-Mei Zeng. New tetraterpenoids from the soft coral Sarcophyton tortuosum. Journal of Asian Natural Products Research, 2007, 9(3), 267-271.
  69. Hou-Jin Li*, Wen-Jian Lan, Chuang-Hua Cai, Yi-Pin Zhou, Yong-Cheng Lin. The Bioactive Pigments from Marine Bacteria Pseudomonas sp.. NATURAL PRODUCTS-Essential Resources for Human Survival, World Scientific Publishing Company, Feburary, 2007, 188-194.
  70. Wen-Jian Lan, Hou-Jin Li*. New Bioactive Triterpenoid from Oldenlandia cantonensis How. Frontiers of Chemistry in China, 2007, 2(3), 307–310.
  71. 蓝文健,莫林峰,蔡创华,周毅频,姚骏骅,李厚金*. 海洋新细菌Zooshikella sp. SY01的培养条件研究. 永利集团3044noc登录入口学报,2007, 46(6), 55-58.
  72. Hou-Jin Li*, Wen-Jian Lan, Chuang-Hua Cai, Yi-Pin Zhou, Yong-Cheng Lin. Biotransformation of limonene by marine bacteria. Chinese Journal of Analytical Chemistry, 2006, 34(7), 946-950.
  73. 蓝文健,李厚金*,蔡创华,周毅频,林永成. 海洋细菌Aeromonas hydrophilaVibrio vulnificus对单萜柠檬烯的生物转化产物分析. 永利集团3044noc登录入口学报,2006, 45(2), 126-128.
  74. 蓝文健,李厚金*. 甜草Oldenlandia cantonensis How的化学成分. 应用化学,2006, 23(8), 871-874.
  75. Xiong-Yu Wu, Xiao-Hong Liu, Yong-Cheng Lin, Jing-Hui Luo, Zhi-Gang She, Hou-Jin Li, Wing-Lai Chan, Sandor Antus, Tibor Kurtan, Brigitta Elsasser, Karsten Krohn. Xyloketal F: A strong L-calcium channel blocker from the mangrove fungus Xylaria sp. (#2508) from the South China Sea coast, European Journal of Organic Chemistry, 2005, (19), 4061-4064.
  76. 李厚金*,蓝文健,林永成. 海洋真菌Hypoxylon oceanicum对1, 2, 3, 4 -四氢萘的转化及其产物测定. 分析测试学报,2005, 24(4), 45-47.
  77. 李厚金*,蓝文健,姚骏骅,林永成. 高效液相色谱-电喷雾串联质谱法确证海洋微生物产生的新环肽的连接顺序. 分析测试学报,2005, 24(5), 46-49.
  78. 温露,袁保红,李厚金,林永成,陈荣礼,周世宁. 南海海洋细菌Pseudomonas sp.的一种抗肿瘤蓝色素. 永利集团3044noc登录入口学报,2005, 44(4), 63-65.
  79. Hou-Jin Li, Yong-Cheng Lin, Jun-Hua Yao, L. L. P. Vrijmoed, E. B. Gareth Jones. A new cytotoxic sterol produced by an endophytic fungus from Castaniopsis fissa from the South China Sea. Chinese Chemical Letters, 2004, 15(4), 419-422.
  80. Hou-Jin Li, Yong-Cheng Lin, Jun-Hua Yao, L. L. P. Vrijmoed, E. B. Gareth Jones. Two new metabolites from the mangrove endophytic fungus No.2524. Journal of Asian Natural Products Research, 2004, 6(3), 185-191.
  81. 李厚金*,林永成. 麦角甾醇及其衍生物的氢化学位移溶剂效应. 分析测试学报,2004, 23(3), 26-30.
  82. 李厚金,陈意光,林永成. 一步法合成活性多羟基甾醇. 永利集团3044noc登录入口学报(自然科学版),2004, 43(3), 126-128.
  83. 李厚金,蔡创华,周毅频,林永成. 大亚湾海洋细菌Pseudomonas sp.中的红色素. 永利集团3044noc登录入口学报(自然科学版),2003, 42(3), 102-104.
  84. 李厚金,姚骏骅,陈意光,林永成,L.L.P. Vrijmoed. 红树林内源真菌2524号中分离的新神经酰胺. 永利集团3044noc登录入口学报(自然科学版),2003, 43(6), 132-133.
  85. Yong-Cheng Lin, Hou-Jin Li, Guang-Ce Jiang, Shi-Ning Zhou, L. L. P. Vrijmoed, E. B. G. Jones. A novel gamma-lactone, eutypoid-A and other metabolites from marine fungus Eutypa sp. (#424) from the south China sea. Indian Journal of Chemistry, Section B, 2002, 41(7), 1542-1544.
  86. 李厚金,林永成,刘晓红,周世宁,L.L.P. Vrijmoed. 红树林内源真菌2524号的肽类成分(I). 永利集团3044noc登录入口学报(自然科学版),2002, 41(1), 110-112.
  87. 李厚金,林永成,刘晓红,周世宁,L.L.P. Vrijmoed. 南海海洋真菌Fusarium sp. (#2489)的代谢产物. 海洋科学,2002, 26(3), 57-59.
  88. 李厚金,林永成,王立. 南海海洋真菌Hypoxylon oceanicum (326#)的代谢产物. 永利集团3044noc登录入口学报(自然科学版),2001, (4), 70-72+80.
  89. 李厚金,巫中德,林永成. 柳珊瑚酸的研究进展. 中国海洋药物,1998, (4), 21-25.

 

专利申请:

  1. 黎孟枫,蓝文健,袁洁,李厚金,于暕辰,郭永卫。吲哚生物碱在制备抗寨卡病毒和/或抗登革病毒药物中的应用。中国发明专利号:ZL202010771165.4;申请日:2020年8月3日,授权公告日:2022年2月8 日。
  2. 李厚金,蓝文健,吴冬兰。一种提高微生物产吲哚喹唑啉类活性生物碱化合物的方法与应用。中国发明专利号:ZL201810714061.2,申请日:2018年6月29日,授权公告日:2021年7月13日。
  3. 李厚金,王坤腾,蓝文健,王来友。一种黄酮化合物的微生物羟基化转化方法与应用。中国发明专利号:ZL201410633262.1,申请日:2014年11月12日,授权公告日:2017年10月27日。
  4. 李厚金,蓝文健,蒋文涵,朱孝峰,冯公侃,钱小军。一种抗肿瘤化合物Chondrosterin J及其制备方法与应用。中国发明专利号:ZL201310692093.4,申请日:2013年12月18日,授权公告日:2015年6月10日。
  5. 蓝文健,李厚金,谢莹璐。化合物及其在制备抗肿瘤药物中的应用。中国发明专利号:ZL201110148628.2,申请日:2011年6月3日,授权公告日:2013年12月11日。
  6. 李厚金,蓝文健,朱孝峰,邓蓉、杨芬。Hirsutanol A在制备抗肿瘤药物中的应用。中国发明专利号:ZL200910037541.0,申请日:2009年3月3日,授权公告日:2011年9月21日。
  7. 李厚金,蓝文健。间二硝基苯的微生物生物转化方法及间硝基苯胺间苯二胺的制备方法。中国发明专利号:ZL200810218879.1,申请日:2008年11月4日,授权公告日:2011年9月21日。
  8. 林永成,吴雄宇,佘志刚,李厚金,刘晓红,罗景慧,周世宁,王焕章,瞿东方,关利平。一种化合物的制备方法及其应用。中国发明专利号:200310111830.3,申请日:2003年10月20日,授权日:2006年4月19日。
  9. 林永成,李厚金,周世宁,佘志刚,关利平。抗肿瘤化合物及其制备方法和制药用途。中国发明专利号:02134711.5,申请日:2002年9月12日,授权日:2004年7月21日。
  10. 林永成,陈光英,佘志刚,李厚金。一种海洋真菌培养物的提取物及其用途。中国发明专利号:02134966.5,申请日:2002年10月17日,授权日:2005年6月15日。

 

主要教改论文:

1.李厚金*,肖华*,黎懿漳,洪凯楠,余静怡,陈六平,朱芳. 美味的化学奥秘——奇妙的美拉德反应. 大学化学, 2023, 38(4), 22-34.

2.陈国胜, 王少涵, 陈月媚, 谢浩志, 肖华, 陈滔, 于禄丹, 李厚金, 朱芳, 欧阳钢锋。固相微萃取联用气相色谱-质谱法快速分析水中痕量苯系物。大学化学, 2022, 37(5), 2111066.

3.胡水, 李厚金*, 赖瑢, 朱可佳, 彭敏, 李莲云. 黄酮化合物脱水闭环反应的研究进展. 大学化学, 2022, 37 (7), 2109051.

4.李厚金*, 陈六平, 张树永. 化学新创实验的现状与发展对策. 大学化学, 2022, 37 (2), 2108010.

5.胡水, 赖瑢, 李厚金, 朱可佳, 周磊, 邵光. 非那西丁的合成与复方阿司匹林的主成分定性分析——推荐一个有机化学实验. 大学化学, 2021, 36 (12),  2103014.

6.李厚金*, 李金珊, 陈六平. 过氧化氢:小分子,大作用. 大学化学,2021, 36 (6), 2006034.

7.李厚金*,许阳,钟云竹,章笑研,朱芳,陈六平. Ugi四组分一锅法高效合成结构独特的活性生物碱化合物. 大学化学, 2020, 35 (4), 178-186.

8.赖瑢,李厚金*,林志强,庞冀燕,邵光,赵晓丹,朱可佳,陈六平. 创新完善集体备课制度,提升有机化学实验教学质量. 大学化学, 2020, 35 (7), 8-12.

9.赖瑢, 朱可佳, 李厚金, 许先芳. 基于RAMP安全原则的有机化学实验安全教育探索. 大学化学, 2020, 35 (7), 123-129.

10.李厚金*, 陈六平. 我国化学科普的现状与创新发展对策. 大学化学, 2020, 35 (11), 1-8.

11.李厚金*,陈六平,朱芳. 科教融合推进化学实验教学改革. 2019新时代高校化学化工教学改革与创新研讨会论文集. 高等教育出版社,北京. 出版时间:2020年4月. ISBN: 978-7-89510-704-5.

12.李厚金*,邱立勤,曾锋,曹日晖,刘高峰,赖瑢,朱可佳,郑赛利,陈六平. 有机天然产物化学实验的教学改革与实践. 大学化学, 2019, 34 (9), 37-43.

13.李厚金*,陈六平. 有机化学实验教学中学生科学探究能力的培养. 大学化学, 2018, 33 (10), 13-17.

14.李厚金*,陈六平. 有机化学实验教学方法探索与实践. 大学化学, 2018, 33 (1), 7-11.

15.李厚金*, 赖瑢,朱可佳,张利,陈六平. 基础有机化学实验教学内容的改革探索. 大学化学, 2017, 32 (4), 21-24.

16.李晓洁,李厚金*,赖瑢,朱可佳,李莲云. 一步法绿色氧化环己烷制备己二酸的研究进展. 大学化学, 2016, 31 (5), 1-7.

17.李厚金*, 朱可佳, 郑赛利, 陈六平. 2-苯基吲哚的合成——推荐一个大学有机化学实验. 大学化学, 2014, 29 (5), 75-78.

18.李厚金*,朱可佳,陈六平. 黄酮化合物的合成——推荐一个大学有机化学实验. 大学化学, 2013, 28 (5), 47-50.

 

著作:

1. 李厚金,石建新,邹小勇。《基础化学实验(第二版)》。北京:科学出版社,2015年6月。

2. 李厚金,副主编,《海洋生物活性化合物手册》,化学工业出版社,2006年7月。

3. 李厚金,海洋真菌的代谢产物,p224-293,见林永成主编《海洋微生物及其代谢产物》第七章,化学工业出版社,2003年1月。